sirolimus

Not strange, maybe, but that fact that orthodox doctors were testing out grapefruit juice on cancer cases is little short of amazing! The study’s main finding was that grapefruit juice might allow treatment using smaller drug dosages, therefore reducing side effects and perhaps costs. Sirolimus (Rapamune) is an immunosuppressant and not approved as a cancer drug. Its primary use is to prevent rejection after kidney transplants. Some early studies suggest that sirolimus may have tumor-fighting effects. Derivatives of the drug are used in kidney cancer and breast cancer. But sirolimus has poor bioavailability, meaning it isn’t absorbed well and not much gets into the blood (14% or so). When grapefruit juice is taken concomitantly, absorption was much higher. Do as well as increasing the benefits of this drug, it could allow lower doses and hence cost saving.

Not strange, maybe, but that fact that orthodox doctors were testing out grapefruit juice on cancer cases is little short of amazing! The study’s main finding was that grapefruit juice might allow treatment using smaller drug dosages, therefore reducing side effects and perhaps costs. Sirolimus (Rapamune) is an immunosuppressant and not approved as a cancer drug. Its primary use is to prevent rejection after kidney transplants. Some early studies suggest that sirolimus may have tumor-fighting effects. Derivatives of the drug are used in kidney cancer and breast cancer. But sirolimus has poor bioavailability, meaning it isn’t absorbed well and not much gets into the blood (14% or so). When grapefruit juice is taken concomitantly, absorption was much higher. Do as well as increasing the benefits of this drug, it could allow lower doses and hence cost saving.